In 1996, at age 47, I was diagnosed with prostate cancer. The urologist to whom I was referred by my new doctor recommended several months of Lupron followed by a radical prostatectomy, which I knew (from searching the internet) was the correct protocol at the time. In conference with my wife and I, however, the urologist warned that several months of Lupron to shrink the tumor might result in side effects, including hot flashes. He mentioned that, in rare cases, breast growth sometimes results.
On hearing that estrogen would take over as testosterone faded from my system, my wife's first question to the doctor was, "Will he finally enjoy shopping with me at the mall?"